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Image Search Results
Journal: Proceedings of the National Academy of Sciences of the United States of America
Article Title: Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
doi: 10.1073/pnas.0711119105
Figure Lengend Snippet: Low doses of osteocalcin increase insulin secretion and β cell proliferation in WT mice. Analyses were performed in mice implanted with osmotic pumps infusing the indicated doses of osteocalcin (Ocn) or vehicle for 14 days (A) and 28 days (A–E). (A) Blood glucose (random feeding). (B) Serum insulin. (C) GSIS. (D) GTT. (E) Quantification of Ki67 immunoreactive cells in pancreatic islets. Results are mean values ± SEM. *, P < 0.05; **, P < 0.01 (Ocn vs. vehicle, Student's t test). a, P < 0.05 (Ocn 0.3 ng/h vs. vehicle); b, P < 0.05 (ANOVA) (Ocn 3 ng/h vs. vehicle). Six to 20 mice per group were analyzed.
Article Snippet: Sections were immunostained with a
Techniques:
Journal: Small (Weinheim an der Bergstrasse, Germany)
Article Title: Capsaicin Enhanced the Efficacy of Photodynamic Therapy Against Osteosarcoma via a Pro-Death Strategy by Inducing Ferroptosis and Alleviating Hypoxia.
doi: 10.1002/smll.202306916
Figure Lengend Snippet: Figure 8. Evaluation and biosafety of different treatments. A) H&E staining and images of PCNA, Ki67, TRPV1, Gpx4, and HIF-1𝛼. IHC staining in tumor specimens after various treatments (scale bar = 100 μm). B–F) IOD values in various groups were analyzed by processing IHC staining through ImagePro Plus. G) Triple IF staining of TRPV1 (red), Gpx4 (orange), and HIF-1𝛼(green) in tumor specimens after various treatments (scale bar = 50 μm). H) TUNEL staining of tumor sections after various treatments (scale bar = 50 μm). I) H&E staining of major organs of mice after different treatments (scale bar = 100 μm). J) Hematological and blood biochemical tests of mice after various treatments.
Article Snippet: Mouse anti-human TRPV1 (cat. 66983-1-Ig), mouse anti-human NQO1 (cat. 67240-1-Ig), rabbit anti-human GCLM (cat. 14241-1-AP),
Techniques: Staining, Immunohistochemistry, TUNEL Assay